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To reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments. Twenty-five patients with reduction in LDL-C had mean response of 20 range of to 53 median of 24 the remaining patients had to 24 increases in LDL-C. Geriatric In elderly subjects age 65 to 80 years irbesartan elimination half-life was kjop billige avalide not significantly altered, but AUC and Cmax values were about 20 to 50 greater than those of young subjects age 18 to 40 years. Oligohydramnios was also reported, presumably from decreased fetal renal function. It may be used alone or in combination with other antihypertensive agents. The terminal elimination half-life of irbesartan averaged 11 to 15 hours.

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