In single-dose study using 14C-labeled Buspirone, 29 to 63 of the dose was excreted in the urine within 24 hours, primarily as fecal excretion accounted for 18 to 38 of the dose. The absence of warning for given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Other Psychotropics Because the effects of concomitant administration of Buspirone with most other psychotropic drugs have not been studied, the concomitant use of Buspirone with other CNS-active drugs should be approached with caution. Buspirone has no significant affinity for benzodiazepine receptors and does not affect GABA binding in vitro or in vivo when tested in preclinical models. If the two drugs are to be used in combination, low dose of buspirone eg,. nusipirkti nebrangiai buspirone Clinical Laboratory Infrequent were increases in hepatic aminotransferases SGOT, SGPT rare were eosinophilia, leukopenia, and thrombocytopenia.