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This finding was confirmed in vivo by clinical drug interaction study in which venlafaxine did not inhibit the metabolism of caffeine, CYP1A2 substrate. What are the possible side effects of Cymbalta? The most common side effect of Cymbalta was nausea. Incidence is based on the number of men Effexor XR 454, placebo 357. The clinical significance of elevated 2-OH-desipramine levels is unknown. In all premarketing major depressive disorder trials with Effexor immediate release seizures were reported at various doses in. Venlafaxine-induced serotonin syndrome has also been reported when venlafxine has been taken in isolation in overdose. What storage conditions are needed for this medicine? Return to top Keep this medication in the container it came in, tightly pirkti pigius venlafaxine su visa classic closed, and out of reach of children.