The clinical course of histoplasmosis in HIV-infected patients is more severe and usually requires maintenance therapy to prevent relapse. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic rekkefolge eller kjop online itraconazole reactions, or adverse effects. ONGLYZA should not be used for the treatment of type diabetes mellitus or diabetic ketoacidosis. In vitro data suggest that trimetrexate is extensively metabolized by CYP3A4. If clinical signs or symptoms develop that are consistent with liver disease, treatment should be discontinued and liver function testing performed. This information should not be considered complete, up to date, and is not intended to be used in place of visit, consultation, or advice of legal, medical, or any other professional.